IgG Purification Resin and Columns

Immunoglobulin G (IgG) Represents approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. Each IgG has two antigen binding sites. Human IgG1 and IgG3 are highly active in initiating Antibody Dependent Cell-Mediated Cytotoxicity (ADCC) and Complement Dependent Cytotoxicity (CDC). In contrast, IgG2 and IgG4 are much less capable in evoking such an immune response. As a result, IgG1 and IgG3 are the most suitable for therapeutic use against cancer cells.

Part #	Name	Amount	Price
LT-136KIT	LigaTrap Goat IgG Kit	1 Kit	$308.70	Add to Cart



LT-136-1ml KIT	LigaTrap Goat IgG Kit 1ml Column Kit	1ml KIT	$236.25	Add to Cart



LT-136-5ml KIT	LigaTrap Goat IgG Kit 5ml Column Kit	5ml KIT	$840.00	Add to Cart



LT-136	LigaTrap Goat IgG Resin	5 ml	$472.50	Add to Cart



LT-136-MSC	LigaTrap Goat IgG MicroSpin Columns- Qty 10	MSC	$131.25	Add to Cart



LT-136-1x1ml	LigaTrap^® Goat IgG Purification Column	1 ml	$105.00	Add to Cart



LT-136-1x5ml	LigaTrap^® Goat IgG Purification Column	1 x 5 ml	$498.75	Add to Cart



LT-136-3x1ml	LigaTrap^® Goat IgG Purification Column	3 x 1 ml	$309.75	Add to Cart

	LigaTrap Goat IgG Loose Resin Protocol
	LigaTrap Goat IgG Prepacked Column Instructions
	LigaTrap Goat IgG Purification Kit

IgG Yield and Purity

Goat IgG was purified from goat serum for loading over LigaTrap® Purification Resin. It was compared to goat serum loaded over Pierce Protein A Plus, and Thermo Protein G. TheLigaTrap® purified resin demonstrated a static binding capacity comparable with both Protein A and Protein G, with purity >90%. All manufacturer recommended chromatographic protocols were followed.

SDS PAGE

About LigaTrap

LigaTrap® purification kits and resins are convenient and easy-to-use. Simply add the sample to the resin, mix and centrifuge. Not only are LigaTrap® purification protocols simple to follow, but also allow for fast and easy recovery of purified antibodies for screening in your end-use assay. Multiple samples can be processed at the same time, resulting in rapid screening for antibody production. LigaTrap® spin columns only require a pipette and centrifuge, no specialized equipment needed. Each spin column is capable of up to 10 purifications, and each kit has the ability to perform over 100 purifications, making LigaTrap® a cost-effective method for antibody purification.