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Goat IgG Purification Resin and Columns

Immunoglobulin G (IgG) Represents approximately 75% of serum antibodies as the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. Each IgG has two antigen binding sites. Human IgG1 and IgG3 are highly active in initiating Antibody Dependent Cell-Mediated Cytotoxicity (ADCC) and Complement Dependent Cytotoxicity (CDC). In contrast, IgG2 and IgG4 are much less capable in evoking such an immune response. As a result, IgG1 and IgG3 are the most suitable for therapeutic use against cancer cells. LigaTrap also offers the advantages of a milder (more basic) pH than other widely used resins, has little or no leaching, and resin can be reused up to 100 cycles.

Part # Name Amount Price

Goat IgG Mircospin Column Kit w/ Buffers

KIT-10x0.1mL $318.00 Add to Cart
LT-136-1ml KIT

Goat IgG 1mL Prepacked Column Kit w/ Buffers

KIT-1x1mL $244.00 Add to Cart
LT-136-5ml KIT

Goat IgG 5mL Prepacked Column Kit w/ Buffers

KIT-1x5mL $866.00 Add to Cart

Goat IgG Loose Resin-5mL

5mL $487.00 Add to Cart

Goat IgG Loose Resin-10mL

10mL $773.00 Add to Cart

Goat IgG Loose Resin-25mL

25mL $988.00 Add to Cart

Goat IgG Loose Resin-50mL

50mL $1,441.00 Add to Cart

Goat IgG Loose Resin-100mL

100mL $1,809.00 Add to Cart

Goat IgG Microspin Columns without buffers

10x0.1mL $136.00 Add to Cart

Goat IgG Prepacked Purification Column-1mL

1x1mL $109.00 Add to Cart

Goat IgG Prepacked Purification Column-5mL

1x5mL $514.00 Add to Cart

Goat IgG Prepacked Purification Columns-3x1mL

3x1mL $320.00 Add to Cart

Goat IgG Yield and Purity

Goat IgG was purified from goat serum for loading over LigaTrap Purification Resin. It was compared to goat serum loaded over Pierce Protein A Plus, and Thermo Protein G. The LigaTrap purified resin demonstrated a static binding capacity comparable with both Protein A and Protein G, with purity >90%. All manufacturer recommended chromatographic protocols were followed. In addition to increased yields and purity levels, LigaTrap technologies addresses many of the shortfalls related to standard affinity ligands including challenges of elution pH, leaching, proteolysis and repeated sanitization associated with other common purification methodologies.


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