IgG Purification Resin and Columns
Immunoglobulin G (IgG) Represents approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. Each IgG has two antigen binding sites. Human IgG1 and IgG3 are highly active in initiating Antibody Dependent Cell-Mediated Cytotoxicity (ADCC) and Complement Dependent Cytotoxicity (CDC). In contrast, IgG2 and IgG4 are much less capable in evoking such an immune response. As a result, IgG1 and IgG3 are the most suitable for therapeutic use against cancer cells.
Part # | Name | Amount | Price | |
LT-136KIT | LigaTrap Goat IgG Kit |
1 Kit | $308.70 | Add to Cart |
LT-136-1ml KIT | LigaTrap Goat IgG Kit 1ml Column Kit |
1ml KIT | $236.25 | Add to Cart |
LT-136-5ml KIT | LigaTrap Goat IgG Kit 5ml Column Kit |
5ml KIT | $840.00 | Add to Cart |
LT-136 | LigaTrap Goat IgG Resin |
5 ml | $472.50 | Add to Cart |
LT-136-MSC | LigaTrap Goat IgG MicroSpin Columns- Qty 10 |
MSC | $131.25 | Add to Cart |
LT-136-1x1ml | LigaTrap® Goat IgG Purification Column |
1 ml | $105.00 | Add to Cart |
LT-136-1x5ml | LigaTrap® Goat IgG Purification Column |
1 x 5 ml | $498.75 | Add to Cart |
LT-136-3x1ml | LigaTrap® Goat IgG Purification Column |
3 x 1 ml | $309.75 | Add to Cart |
IgG Yield and Purity
Goat IgG was purified from goat serum for loading over LigaTrap® Purification Resin. It was compared to goat serum loaded over Pierce Protein A Plus, and Thermo Protein G. TheLigaTrap® purified resin demonstrated a static binding capacity comparable with both Protein A and Protein G, with purity >90%. All manufacturer recommended chromatographic protocols were followed.