IgG Purification Resin and Columns
Immunoglobulin G (IgG) Represents approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. Each IgG has two antigen binding sites. Human IgG1 and IgG3 are highly active in initiating Antibody Dependent Cell-Mediated Cytotoxicity (ADCC) and Complement Dependent Cytotoxicity (CDC). In contrast, IgG2 and IgG4 are much less capable in evoking such an immune response. As a result, IgG1 and IgG3 are the most suitable for therapeutic use against cancer cells.
| Part # | Name | Amount | Price | |
| LT-136KIT | LigaTrap Goat IgG Kit |
1 Kit | $294.00 | Add to Cart |
| LT-136 | LigaTrap Goat IgG Resin |
5 ml | $450.00 | Add to Cart |
| LT-136-1x1ml | LigaTrap® Goat IgG Purification Column |
1 ml | $100.00 | Add to Cart |
| LT-136-1x5ml | LigaTrap® Goat IgG Purification Column |
1 x 5 ml | $475.00 | Add to Cart |
| LT-136-3x1ml | LigaTrap® Goat IgG Purification Column |
3 x 1 ml | $295.00 | Add to Cart |
IgG Yield and Purity
Goat IgG was purified from goat serum for loading over LigaTrap® Purification Resin. It was compared to goat serum loaded over Pierce Protein A Plus, and Thermo Protein G. TheLigaTrap® purified resin demonstrated a static binding capacity comparable with both Protein A and Protein G, with purity >90%. All manufacturer recommended chromatographic protocols were followed.
