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Prepacked Purification Columns

Currently, chromatography production column binding capabilities are not fully used, hold times are long, and equipment only runs a small percentage of the time.  Many solutions are being investigated to improve the bioseparations platform including cycle life of production columns and continuous multicolumn processes.  The LigaTrap resins can be purchased in a prepacked column to improve purification for monoclonal antibodies.

Unlike filtering of contaminants by size exclusion technology, LigaTrap Columns use stable ligands and in cleaning protocols has harsher base sanitation than in other chromatography products.  Column life cycle is typically well over 50 cycles and well preserved despite more thorough cleaning.  These attributes result in low cost prepossessing step per cycle of use.  The columns capture wider ranges of impurities and undesired molecules protecting the more expensive production columns from them.  Therefore, being more robust than Protein A or G for purification, this preprocessing lowers costs of the production column because of fewer impurities and lowering the sample volume.  Columns are adaptable to continuous bioprocessing by being placed in the production line as a preprocessing step.

LigaTrap column residence time requirements are relatively short at 1 to 5 minutes.  In one study, “not only did the researchers find that the platform would reduce equipment costs by more than 55%, footprint by 32%, water use by 85%, buffer requirements by 58%, and overall time by 45%, but that it reduced overall unit operation costs by 21% at the 3-kg level, and by 29% at the 15-kg level, suggesting continuous downstream processes’ potential.”

The LigaTrap Prepacked Purification Column is the solution.

Contact our scientists for more information.

Part # Name Amount Price
LT-136-1x1ml Goat IgG Prepacked Purification Column-1mL 1x1mL $105.00 Add to Cart
LT-136-1x5ml Goat IgG Prepacked Purification Column-5mL 1x5mL $498.75 Add to Cart
LT-136-3x1ml Goat IgG Prepacked Purification Columns-3x1mL 3x1mL $309.75 Add to Cart
LT-095-1x1ml Human IgG Prepacked Purification Column-1mL 1x1mL $105.00 Add to Cart
LT-095-1x5ml Human IgG Prepacked Purification Column-5mL 1x5mL $498.75 Add to Cart
LT-095-3x1ml Human IgG Prepacked Purification Columns-3x1mL 3x1mL $309.75 Add to Cart
LT-137-1x1ml Mouse IgG Prepacked Purification Column-1mL 1x1mL $105.00 Add to Cart
LT-137-1x5ml Mouse IgG Prepacked Purification Column-5mL 1x5mL $498.75 Add to Cart
LT-137-3x1ml Mouse IgG Prepacked Purification Columns-3x1mL 3x1mL $309.75 Add to Cart
LT-139-1x1ml Rabbit IgG Prepacked Purification Column-1mL 1x1mL $105.00 Add to Cart
LT-139-1x5ml Rabbit IgG Prepacked Purification Column-5mL 1x5mL $498.75 Add to Cart
LT-139-3x1ml Rabbit IgG Prepacked Purification Columns-3x1mL 3x1mL $309.75 Add to Cart
LT-138-1x1ml Rat IgG Prepacked Purification Column-1mL 1x1mL $105.00 Add to Cart
LT-138-1x5ml Rat IgG Prepacked Purification Column-5mL 1x5mL $498.75 Add to Cart
LT-138-3x1ml Rat IgG Prepacked Purification Columns-3x1mL 3x1mL $309.75 Add to Cart
LT-141-1x1ml LigaTrap Sheep IgG Purification Column 1 ml $105.00 Add to Cart
LT-141-1x5ml LigaTrap Sheep IgG Purification Column 1 x 5 ml $498.75 Add to Cart
LT-141-3x1ml LigaTrap Sheep IgG Purification Column 3 x 1 ml $309.75 Add to Cart
LT-144-1x1ml Llama IgG Prepacked Purification Column-1mL 1x1mL $105.00 Add to Cart
LT-144-1x5ml Llama IgG Prepacked Purification Column-5mL 1x5mL $498.75 Add to Cart
LT-144-3x1ml Llama IgG Prepacked Purification Columns-3x1mL 3x1mL $309.75 Add to Cart



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