
for IgM and IgG on the market today.

for LigaGuard HCP absorbent technology.
TOP SELLING PRODUCTS
HUMAN IgM
LigaTrap’s IgM affinity chromatography purification resins have been proven to be superior in the industry, making the purification of IgM straightforward, affordable and lab efficient. IgM resin has the advantages of extended cycle lives and a milder more basic elution compared to other commonly used resins.
LIGAGUARD
LigaTrap’s newly introduced affinity adsorbant, LigaGuard, is a proprietary ensemble of multi-modal ligands which is capable of capturing host cell proteins (HCPs) and DNA selectively in flow-through (continuous) mode. The nature of our resin allows desired bio-products to progress, unbound, with a high purity and recovery.
HUMAN IgG
LigaTrap’s Human IgG resin has advantages over other modalities in its ability to capture all IgG subclasses including being superior for IgG1 and IgG2. The resin elutes at a milder pH of 4.0, reducing precipitation and aggregation. It is able to perform well for 50 cycles making it very cost effective.
“We have been using LigaTrap mouse IgM purification resin and their custom purification service for two years. The elution buffer is mild, pH3.8, which is a plus for keeping the antibody’s antigen binding ability. In addition, we were very satisfied with the purity and recovery rate of purified IgM from the serum-free hybridoma culture supernatants and their custom purification service.”
The Feinstein Institute for Medical Research
“Searched for affinity chromatography columns/resins to purify antibodies with rat Fc groups, we have found only LigaTrap ratIgG column works. In addition, LT columns can be CIPed with 0.5M NaOH. Purification protocol provided and kind customer service are extra. I strongly recommend LigaTrap ratIgG for rat antibody purification.”
“I am very pleased with the Mouse IgM kit. The sales and technical support teams promptly respond to my queries.”

Purification of mAb Therapeutics by Continuous Chromatography
Presented by
Stefano Menegatti, PhD

Novel Ligands and Modalities for Purifying Gene-editing Products: CRISPR and Viral Vectors
Stefano Menegatti & BioPep Team

Removal of host cell proteins from cell culture fluids by weak partitioning chromatography using peptide-based adsorbents
R. Ashton Lavoie & Group

Purification of mAb Therapeutics by Continuous Chromatography
Presented by
Stefano Menegatti, PhD

The Forgotten Immunoglobulin LigaTrap Technologies and Advancements in IgM Purification
Tee Bordelon, PhD, et al

Bioprocess Tools & Designs for the Purification of Viral Vectors for Gene Therapy
Stefano Menegatti & Group