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Human IgG Purification Resin and Columns

Immunoglobulin G (IgG) represents approximately 75% of serum antibodies in humans and is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells with each IgG molecule possessing two antigen binding sites. The four subclasses of Human IgG are IgG1, IgG2, IgG3, and IgG4 – each of which plays its own role in eliciting immune system responses and is used for a variety of therapeutic research. LigaTrap  Human IgG Purification products are capable of purifying all 4 subclasses.

In addition to increased yields and purity levels, LigaTrap Technologies address many of the shortfalls related to standard affinity ligands including challenges.  Our peptide ligands provide for a robust lifecycle, mild elution conditions and no immunogenicity or leaching.

Part # Name Amount Price
LT-095KIT

LigaTrap Human IgG Kit

1 Kit $308.70 Add to Cart
LT-095-1ml KIT

LigaTrap Human IgG 1ml Column Kit

1ml KIT $236.25 Add to Cart
LT-095-5ml KIT

LigaTrap Human IgG 5ml Column Kit

5ml KIT $840.00 Add to Cart
LT-095

LigaTrap Human IgG Resin

5 ml $472.50 Add to Cart
LT-095-10ml

LigaTrap Human IgG Resin

10ml $750.00 Add to Cart
LT-095-25ml

LigaTrap Human IgG Resin

25ml $959.20 Add to Cart
LT-095-50ml

LigaTrap Human IgG Resin

50ml $1,398.20 Add to Cart
LT-095-100ml

LigaTrap Human IgG Resin

100ml $1,756.00 Add to Cart
LT-095-MSC

LigaTrap Human IgG MicroSpin Columns- Qty 10

MSC $131.25 Add to Cart
LT-095-1x1ml

LigaTrap Human IgG Purification Column

1 ml $105.00 Add to Cart
LT-095-1x5ml

LigaTrap Human IgG Purification Column

1 x 5 ml $498.75 Add to Cart
LT-095-3x1ml

LigaTrap Human IgG Purification Column

3 x 1 ml $309.75 Add to Cart

Human IgG Yield and Purity

Human IgG was purified from CHO spiked media containing PBS and an 80 mg/ml load by passing the sample over LigaTrap Human IgG resin, Pierce Plus Protein A and Pierce Protein G. The LigaTrap purified resin demonstrated a static binding capacity higher than Protein A and purity >95%.  Human IgG subclasses in spiked CHO media with 1% FBS compared to leading competitor Protein A and G demonstrated superior ability of LigaTrap Human IgG to purify IgG1 and IgG2. Three different manufacturer recommended binding conditions were used for the leading competitor of IgM purification resin.  All manufacturer recommended chromatographic protocols were followed.

COMPARABILITY
SDS PAGE


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