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Human IgM Purification Resin and Columns

The LigaTrap technology separates itself by having the highest quality chromatographic purification for IgM on the market today. It captures both antibody subtypes and can be reused after sanitization up to 100 times. With a molecular weight of 990,000 Daltons, IgM is the largest and hardest of the major antibodies commonly purified. IgM has 10 binding domains (compared to 2 for IgG antibodies) creating more affinity for the target. New IgM molecule based therapeutics are being developed as it is understood to have unique properties such as acting that act as the brain of the immune system, being an early responder to antigens and working through the complement system.

IgM monoclonal antibodies have become increasingly favorable for their use as therapeutic tools, while remaining popular for their research and diagnostic applications. Protein A and G prove to be unsuitable for IgM purification proves. LigaTrap Technologies separates itself by having the highest quality chromatographic purification for IgM on the market today. LigaTrap Human IgM Purification Resin captures both antibody subtypes and can be reused after sanitization up to 100 times.

In addition to increased yields and purity levels, LigaTrap Technologies address many of the shortfalls related to standard affinity ligands including challenges. Our peptide ligands provide for a robust lifecycle, mild elution conditions and no immunogenicity or leaching.

Disclaimer: This product is not recommended in serum purification applications due to cross-reactivity with other immunoglobulins. Please consult LigaTrap for protocols that may improve results in serum.

Part # Name Amount Price
LT-143KIT

Human IgM Mircospin Column Kit w/ Buffers

KIT-10x0.1mL $397.95 Add to Cart
LT-143-1ml KIT

Human IgM 1mL Prepacked Column Kit w/ Buffers

KIT-1x1mL $351.75 Add to Cart
LT-143-5ml KIT

Human IgM 5mL Prepacked Column Kit w/ Buffers

KIT-1x5mL $1,050.00 Add to Cart
LT-143

Human IgM Loose Resin-5mL

5mL $733.95 Add to Cart
LT-143-10ml

Human IgM Loose Resin-10mL

10mL $920.00 Add to Cart
LT-143-25ml

Human IgM Loose Resin-25mL

25mL $1,320.00 Add to Cart
LT-143-50ml

Human IgM Loose Resin-50mL

50mL $2,200.00 Add to Cart
LT-143-100ml

Human IgM Loose Resin-100mL

100mL $3,300.00 Add to Cart
LT-143-MSC

Human IgM Microspin Columns without buffers

10x0.1mL $147.00 Add to Cart
LT-143-1x1ml

Human IgM Prepacked Purification Column-1mL

1x1mL $156.45 Add to Cart
LT-143-1x5ml

Human IgM Prepacked Purification Column-5mL

1x5mL $733.95 Add to Cart
LT-143-3x1ml

Human IgM Prepacked Purification Columns-3x1mL

3x1mL $450.45 Add to Cart

Human IgM Yield and Purity

Human IgM was purified from CHO media containing 5% FBS using and a leading competitor of IgM purification resin. Standard chromatographic conditions were used for the LigaTrap Human IgM resin. Three different manufacturer recommended binding conditions were used for the leading competitor of IgM purification resin.

COMPARABILITY
SDS PAGE


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